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Weight of evidence: Overall evidence is ModerateLow : encouraging signal from a historical cross-over trial but limited by small samples and lack of biomarker data

Vitamin D deficiency has been linked to reduced microbial diversity, diminished butyrate production, thinning of the mucus layer, and increased epithelial permeability [31]

Similarly, GPXs inhibition using mercaptosuccinate increased intracellular GSH levels (Supplementary Figure S3D) and the response of H1975 cells to erlotinib (Supplementary Figure S3E)

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