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this is the case for mice with podocyte-specific heterozygous INSR deletion (Madhusudhan et al., 2015)

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737 Under conditions of low glutamine availability, the transcription factor p53 plays a crucial role in prosurvival signaling by stimulating the expression of transporters to increase the uptake of other amino acids, thereby assisting cancer cells in overcoming nutrient scarcity

39,40 In addition to engaging classical Fc receptors on the cell membrane, antibodies exert potent immune functions from inside cells via a unique cytosolic receptor for IgG Fc, which is called TRIM21