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Recent studies suggested that the Orp1-mediated oxidation of Yap1 in yeast requires a third interaction partner, Ybp1, which acts as scaffolding protein [110]

Eye Contact Lens 31 , 186193 (2005)

SCH-C also improved intestinal permeability dysfunction across three IBD model systems by enhancing epithelial barrier integrity through upregulation of ZO-1 and occluding [479]

However, as with other lipid-based nanosystems, key challenges remain, including ensuring long-term formulation stability, evaluating safety with repeated topical application, and scaling up production for clinical-grade batches [123, 124, 134]