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The assembly of salamander genomes is challenging because of its large size and excessive number of repetitive regions (axolotl genome

22 Insulin signaling pathways Physiologically, insulin binds to the extracellular subunit of insulin receptor, a receptor tyrosine kinase which recruits and phosphorates insulin receptor substrate (IRS)-1, thus activating phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt) signaling and diverse downstream pathways to maintain the glucose homeostasis

To examine a novel cell model based on patient-derived cells from the human olfactory neuroepithelium, an elegant study assessed gene and protein expression and cell function from healthy controls, patients with schizophrenia or Parkinsons disease (Matigian et al

Tendon injuries often take longer to heal than other soft tissue injuries