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aeruginosa , a triple-phage cocktail (KIM-C1) comprising phages from distinct CGs achieved 96% killing efficacy against diverse clinical isolates, including biofilm-associated strains, and demonstrated enhanced antibacterial activity when combined with aztreonam in both in vitro assays and murine wound infection models

Moreover, IGF-1R activation downregulates cell cycle suppressors p27 kip1 , p57 kip2 , and PTEN [25, 26], indicating multiple pathways are involved

) following in vitro exposure to pathogenic and probiotic bacterial strains

Examples of vectors for expression in Saccharomyces cerevisiae (S.cerevisiae) include pYepSec1(Baldari et al (1987) EMBO J.6: 229