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This initial phosphorylation cascade leads to autophosphorylation of the carboxy-terminal bidentate substrate-binding site (Tyr1349 and Tyr1356) of the c-Met and these residues have been shown as docking sites for downstream signaling molecules [52]

Ann N Y Acad Sci 1035:85103 Klein DC (2007) Arylalkylamine N -acetyltransferase: the Timezyme

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Unlike conventional hydrogels lacking osteogenic cues, the SF/HAMA dual-network hydrogel combined with DDM particles endows the material with the ability to mimic the hierarchical structure of natural bone, demonstrating both osteoinductive and osteoconductive properties