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Unlike endogenous cannabinoids, THC also increases mitochondrial hydrogen peroxide production [39], and reactive oxygen species (ROS) production and neuronal apoptosis in mPFC [32], a brain region critically involved in neuropsychiatric pathology

511 Mitophagy diminishes insoluble A 1-42 , A 1-40 , and hyper-phosphorylated tau, preventing cognitive or memory impairment in mouse model

The opposite effect occurs at the adult stage (P56P70), during which wild-type mice show robust LTP and LTD compared to MET cKO mice in which LTP and LTD are markedly decreased

Oral glutathione supplements stored at room temperature (25C) lose approximately 25% potency per week