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Abdel Douiri: received funding for the is work from the National Institute for Health and Care Research and the Stroke Association

Factor Xa Factor Xa is a serine protease that specifically cleaves a sequence I(E/D) GRX, where X can be any amino acid except arginine or proline, enabling removal of N-terminal affinity tags with minimal residual amino acids at the target proteins N-terminus [139]

Galley, J

[81] They also show that one of the causes of age-related decline in DNA repair may be increased binding of the protein DBC1 (Deleted in Breast Cancer 1) to PARP1 (poly[ADPribose] polymerase 1) as NAD + levels decline during aging