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Bermejo P, Martin-Aragon S, Benedi J et al

Ethical statement Research with human subjects were conducted in compliance to guidelines: Ethical Regulations for Research Involving Human Subjects and Supplementary Ethical Regulations for Research Involving Human Subjects

In an experimental study, it was found that p38 MAPK plays a role in AR, specifically in the release of Th2 cytokines (Liu et al., 2010)

Figure 1 Furthermore, SAM serves as a methyl donor, methylating DNA and proteins, including histones (Zade et al., 2023), which in turn influences epigenetic regulation, and gene expression ( Figure 1 )