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The agency specifically noted that some patients were told by prescribers or telehealth platforms that topical application carried no risk of systemic side effects

The ADI-R is a comprehensive interview administered to parents that provides a thorough assessment of individuals with ASD (44)

Standard community protocols run tirzepatide alone for the first 8 weeks (2.5 5 mg/week) to confirm GI tolerance, then add cagrilintide at 0.25 mg/week starting Week 9

Consistent with this, we demonstrate that treatment with MK-801, even at doses that do not evoke weight loss, elicits pronounced hyperthermia in DIO mice (Extended Data Fig