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An enlarged prostate, or benign prostatic hyperplasia (BPH), is a common condition characterized by a swollen prostate gland and uncomfortable urinary symptoms

A genome-wide mutational constraint map quantified from variation in 76,156 human genomes

doi: 10.1016/j.mvr.2022.104342 126 SegelM.NeumannB.HillM

In skeletal muscle this pathway can support satellite cell activation and possible hyperplasia (creation of new muscle fibers)

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