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3.4 Changes in serum homocysteine by supplementation route and dosage Analysis of 10 comparisons showed that vitamin B12 supplementation was associated with a mean reduction of 35.8% in serum homocysteine concentrations (Supplementary Table S5)

It may offer neuroprotective, angiogenic, wound healing and tissue growth propertiesand all of these benefits have been noted in preclinical studies, although human research is severely lacking

Maiga M, Agarwal N, Ammerman NC, Gupta R, Guo H, Maiga MC, Lun S, Bishai WR

Severe constipation with abdominal pain, vomiting, or inability to pass gas requires immediate medical attention as it may indicate bowel obstruction, a rare but serious complication