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Oka A, Takagi A, Komiyama E, Yoshihara N, Mano S, Hosomichi K, Suzuki S, Haida Y, Motosugi N, Hatanaka T, Kimura M, Ueda MT, Nakagawa S, Miura H, Ohtsuka M, Tanaka M, Komiyama T, Otomo A, Hadano S, Mabuchi T, Beck S, Inoko H, Ikeda S (2020) Alopecia areata susceptibility variant in MHC region impacts expressions of genes contributing to hair keratinization and is involved in hair loss

IGF-1Eb in rodents) the mechanosensitive splice variant, expressed locally in skeletal muscle in response to stretch, overload, or damage, characterised by a 49 bp insert (52 bp in rodents) within exon 5 that creates a reading frame shift and generates a unique 2425 amino acid C-terminal E-domain peptide distinct from the E-domain of IGF-1Ea The 24-amino acid C-terminal E-domain peptide of IGF-1Ec commonly designated MGF-24aa or MGF E-peptide is the biologically active fragment studied in the majority of synthetic MGF research, including PEG-MGF