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The mTOR agonist MHY1485 partially reverses this protective effect

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While metformin has been demonstrated to improve mitochondrial respiration, it is worth noting that higher doses of metformin have been associated with a contrary effect, namely, reduced mitochondrial respiration

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doi: 10.1089/scd.2010.0093 45 LyCHLynchGSRyallJG

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SMDJ Seychelles Medical and Dental Journal

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