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Description

One underappreciated but critical mechanism by which hyperglycemia promotes HCC progression is through LPA production

Mechanism of Action FOXO4-DRI disrupts the protective interaction between FOXO4 and p53 in senescent cells , allowing damaged cells to undergo apoptosis

Strengthens the skin barrier Barrier disruption worsens pigmentation

The Panel notes that if a clinician chooses to administer a "cocktail" preparation, then he or she should be aware that DMSO potentially enhances absorption of other substances, creating the possibility for toxicity from drugs such as lidocaine