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However, there are some intriguing varia- tions in organisms such as halobacteria, in which GSH can be replaced by other sulphur compounds like g- glutamylcysteine (g-EC) and thiosulphate (Newton & Javor 1985)

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A CIC target binding octamer sequence occurs in the promoter regions of the folate transport genes FR, PCFT, and RFC1, and dihydrofolate reductase, and binding was confirmed by chromatin immunoprecipitation assays