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FIGURE 5 SOMATIC MUTATIONS IN KEAP1 OR NRF2 Missense mutations in the KEAP1 gene have been identified in several human cancers, particularly in solid tumors in the lung, gallbladder and liver (Padmanabhan et al., 2006

Case 3 Mrs J (body weight 70 kg) was diagnosed with congestive heart failure and atrial fibrillation