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Pawlosky, R

Hypomethylation of the PPAR gene, involved in lipid metabolism, increases its expression and stimulates steatosis development [338]

However, the isolation of antioxidant enzymes in their native form is a very cumbersome and cost-intensive approach, apart from other limitations such as potential immunological problems which can arise during their systemic application as therapeutic agents [69]

They can bind to proteins and lipids, stabilize the structure of nerve cells and synapses (Martin, 2002), and are used as a source of cellular energy (Falkowska et al., 2015) and as a neurotransmitter precursor substance (Varki, 2017), which are essential nutrients for the brain (Nelson et al., 2012)