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The Evidence Gap The gap between epitalons claims and its evidence is substantial: longevity claims are based primarily on animal studies and Khavinsons research

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Several important observations about ACE2 expression in the GI tract include: ACE2 is expressed at higher levels in digestive tract organs compared to lungs The small intestine and terminal ileum show the highest expression levels across the body ACE2 expression in gastric tissues increases gradually from chronic gastritis to metaplasia to cancer This receptor distribution pattern creates vulnerability to infection throughout the digestive system