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The clinical trial and correlative analyses were approved by the CHUM Ethics Review Board and each participating center (ethics no

To confirm that mitochondria were in good condition and able to oxidize free fatty acids in a carnitine-dependent manner, free coenzyme A (CoA) and free carnitine were added to skeletal muscle homogenates energized with free hexanoate, free octanoate, or free oleate demonstrating that the addition of CoA and carnitine allowed for robust oxidation of the FFAs (Fig

and Z.H.) working independently and in pairs identified and screened the titles and abstracts of potentially eligible articles

(Lausanne) 5, 85