conjugation of epoxides with glutathione A: to a generic xenobiotic (X) via GST results Glutathione conjugation - Sulfate uptake

Although multiple pathways are involved in mediating tissue damage, including the polyol pathway, advanced glycation end product formation, protein kinase C activation, and the hexosamine pathway, a common feature is increased oxidative stress marked by elevated levels of reactive oxygen species (ROS) (1)

[DOI] [PMC free article] [PubMed] [Google Scholar] 123.Haqqani A.S., Thom G., Burrell M., Delaney C.E., Brunette E., Baumann E., Sodja C., Jezierski A., Webster C., Stanimirovic D.B

M., Harvey, C

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