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Within the caudal corpus callosum, the number of PDGFR+ cells significantly increased when cuprizone was delivered as pellets compared to control pelleted feed (p 0.05

It has been shown that the circadian clock gene, Per2, upregulates BHB synthesis enzymes and FAA, which is abated when the monocarboxylate transporter 1 (MCT1 and SLC16a1), crucial for BHB efflux, is deleted in the liver (Chavan et al., 2016

Mutagenesis 16:203208 Lisanti MP, Martinez-Outschoorn UE, Lin Z, Pavlides S, Whitaker-Menezes D, Pestell RG, Howell A, Sotgia F (2011) Hydrogen peroxide fuels aging, inflammation, cancer metabolism and metastasis: the seed and soil also needs fertilizer. Cell Cycle 10:24402449 Marinho HS, Real C, Cyrne L, Soares H, Antunes F (2014) Hydrogen peroxide sensing, signaling and regulation of transcription factors

The fibrosis index based on four factors (FIB-4) was used as a non-invasive evaluation of liver fibrosis