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Yoon SB et al

An in vitro study suggested that necroptosis is involved in the pathogenesis of PD through excitotoxicity, the accumulation of intracellular Ca 2+ or TNF, although its contribution to PD pathology is uncertain (Beal, 2008

J Biol Chem (2008) 283(2):8028.10.1074/jbc.M704755200 64 IshiiKJKawagoeTKoyamaSMatsuiKKumarHKawaiTet alTANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines