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679 Tert-butylhydroquinone (TBHQ), as an Nrf2 activator, has been shown to activate Nrf2-related pathways in a TBI mouse model by combining vanillin acetate and TBHQ, reducing oxidative stress and protecting gray matter in the mouse brain

Glutathione and its precursors (such as cysteine peptides) are absorbed intestinally and distributed systemically [66], reaching dermal tissues to exert photoprotective and skin-lightening effects, particularly relevant for women concerned with age-related pigmentation changes [74, 75]