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As discussed, various experimental limitations hinder the comprehensive characterization regarding VitB12, such as inducing deficiency or, conversely, supplementation

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Although the mechanism by which oxidizing agents is distinct from ionizing radiation, conditions like severe sepsis and septic shock also create an oxidation-rich environment that leads to the depletion of natural cellular antioxidants (such as glutathione) and contributes to cellular injury and death

As such, we are declining to modify the reporting incentive criteria to require the use of the eCQM collection type for reporting at least 3 of the 4 quality measures with this collection type in the proposed APP Plus quality measure set for the 2025 performance year