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That claim rests largely on a single, genuinely interesting laboratory study: Pyo et al

Other side effects of Zepbound include kidney and gallbladder disease, hypoglycemia, pancreatitis, allergic reactions, injection site reactions, and suicidal thoughts

Taken together, these results suggest high selectivity of the small molecule 5-amino-1MQ analogue at pharmacologically relevant concentrations to NNMT-inhibition