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Such a catalyst was constructed via the coordination of a manganese porphyrin MnTCPP + and Zn 2+ , between which the MnTCPP + provides an active Mn III site with a coordination environment analogous to those of the active metal sites of Mn-SOD and catalase, while Zn 2+ upregulates the redox potential of the coordinated MnTCPP + , making the 2D MOF present considerable SOD- and catalase-like activities

Hypoxia reversal and reactive ROS storm Hypoxia is a prevalent characteristic of solid tumors, primarily caused by aberrant vasculature resulting from rapid tumor proliferation

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