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Moreover, folate is critical for pregnant women to reduce the risk of birth defects.* CARDIOVASCULAR SYSTEM HEALTH* CAN REDUCE RISK OF BIRTH DEFECTS*^ ^Women who consume healthful diets with adequate folate throughout their childbearing years may reduce their risk of having a child with a birth defect of the brain or spinal cord

10.1105/tpc.108.060335 Plant Cell 72 WatanabeM.TohgeT.FernieA

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Cellular reprogramming of fibroblasts, blood cells, and urine-derived epithelial cells from FAD and SAD patient donors into iPSCs and then re-differentiation to neurons is advantageous because it allows for a detailed molecular examination of the disease pathophysiology and targeted therapeutic intervention [145, 146]