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Comment on the provisional report from the WHO consultation

In neurons, recycling of BDNF enables, on the one hand, the replenishment of the BDNF pool of releasing cells and re-use of BDNF after further processing steps

[3] Here, we will discuss several putative nootropics of interest, spanning these categories with a special focus on lesser-known, novel approaches to cognitive enhancement

28 Co-occurring conditions like anxiety, depression, stress, and sleep disorders can be contributors, while disturbances that are difficult to diagnose, such as dysregulated stress reactivity, neurotransmitter imbalance, inflammation, mitochondrial dysfunction, free radical damage, hormonal imbalance, and metabolic disturbance, as well as crosstalk between these factors, may also play a role