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Approved Use While tesamorelin has FDA approval, it's important to understand the regulatory framework: On-label (approved): Prescription Egrifta for HIV-associated lipodystrophy Off-label: Any use outside the approved indication (physicians may prescribe off-label, but this is not FDA-endorsed) Research use: Laboratory-grade tesamorelin for investigational purposes Compounding Regulations Because tesamorelin IS FDA-approved (unlike BPC-157 or TB-500), compounding rules differ