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Heat-sterilized Bifidobacterium breve prevents depression-like behavior and interleukin-1beta expression in mice exposed to chronic social defeat stress

51 Cicarelli, G

Mice treated with the peptide performed much better in a task that required learning to navigate a water maze, which relies on spatial memory, than mice that were treated with a control peptide (a scrambled version of the peptide used to inhibit CDK5-P25)

HK-2 cells were cultured at 37C in a humidified atmosphere with 5% CO2 until 80% confluency in DMEM (Nissui Corporation) containing 10% fetal bovine serum (Serana Europe GmbH), 100 units/ml penicillin and 100 g/ml streptomycin