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Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism

The polar and charged residues lining the enzymes binding pocket likely contribute to the formation of an electrostatic environment essential for substrate interaction (Suyal et al., 2023)

*Correspondence: Yanling Hao, [email protected] This article was submitted to Microbial Physiology and Metabolism, a section of the journal Frontiers in Microbiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

7-selective type II positive modulators can disrupt the desensitized state and facilitate the opening of ion channels