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Given that orally administered prebiotics and postbiotics have been shown to improve pulmonary health in calvespotentially through modulation of the gut lung axisthe oral microbiome, as a nodal point within this axis, represents an accessible intervention point warranting further investigation in bovine-specific models

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However, a sex-specific effect was observed, with reduced cancer incidence and mortality in men but not in women, potentially linked to lower baseline antioxidant status in men, particularly -carotene levels (347)

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