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For example, Nadatani in 2016 reported that caspase-1 can induce pyroptosis, a unique form of programmed cell death, through the conversion of pro-IL1 and pro-IL18 in their active forms, which promotes further inflammation

The endotoxin hypothesis of Alzheimers disease

Similarly, the activity of the selenium-containing glutathione peroxidase enzyme, responsible for speeding up the reaction between glutathione and free radicals (such as hydrogen peroxide) will be negatively affected if dietary selenium is low and enhanced when selenium is high

The protective effects of L -carnitine on myocardial ischaemia-reperfusion injury in patients with rheumatic valvular heart disease undergoing CPB surgery are associated with the suppression of NF-kappaB pathway and the activation of Nrf2 pathway