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Wikipedia Insulin-like Growth Factor 1 (IGF-1) Comprehensive overview of IGF-1 biology, receptor interaction, and cellular signalling

The latter in response to stimulation by intestinal microbial antigens, particularly LPS, upregulate the production of proinflammatory cytokines (e.g., IL-1, IL-6, TNF) and reactive oxygen species (ROS), contributing to the enhancement of pro-inflammatory reactions (Van Spaendonk et al., 2017)