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Modern surgical recovery protocols increasingly recognize that the quality and speed of healing depend not just on surgical technique, but also on providing the cellular environment and molecular signals necessary for optimal tissue repair

There is clear evidence that deficiencies in the function of insulin/IGF-1 signaling can extend lifespan, whereas an increased activity in this pathway promotes the aging process

They recapitulate well the systemic disease with the exception of pancreatic and liver disease and spontaneous lung disease

Like the duo above, it prompts the pituitary to produce more of your own growth hormone