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Jabs S, Biton A, Bcavin C, Nahori MA, Ghozlane A, Pagliuso A, et al

The genes normal function may be altered if it produces too many copies of itself (a process known as gene amplification) or too many copies of HER2 receptors (overexpression)

The thinning and sometimes detachment of the SV seen in the KI mice was reported in a mouse with a conditional deletion of Hgf exon 6 and in a constitutively overexpressing Hgf mouse (MH19) (Takayama et al., 1996