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platensis , with a particular focus on their ability to modulate cytokine production on LPS-stimulated RAW264.7 cells

In order to test this possibility, we engineered a murinized version of the anti-IGF-1R mAb, L2-C (L2-Cmu), in order to reduce effector function and enable chronic administration in mice

Importantly, pharmacological GCL inhibition hindered lymphoma growth in female -MYC mice, suggesting that this treatment holds promise as a therapeutic strategy for female lymphoma/leukemia patients