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J Clin Invest 123(9):36783684 Herranz D, Ambesi-Impiombato A, Sudderth J et al (2015) Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia

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However, this flexibility comes at the cost of stability, which is maintained by a group of muscles known as the rotator cuff, because they are arranged like a cuff around the shoulder