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They demonstrated that this platform elevated extracellular ATP (eATP) levels, which triggered the activation of the P2X7-NLRP3-inflammasome to drive macrophage pyroptosis and potentiated the maturation and antigen capacity of DCs

Vi ng ngm, tinh khit v cng ngh mng bao gip phn t thm qua nim mc mi l yu t quyt nh

Macrophages of the vascular wall can collect iron, and iron overload in turn causes macrophages to transition to an anti-inflammatory phenotype, which leads to inflammation, oxidative stress, and increased plaque formation

If 1 mM or 15 mM carnitine was added before the omeprazole, surprisingly, the inhibition increased to 80% and 92%, indicating that the omeprazole reaction with the transporter was not protected but facilitated by the presence of carnitine