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Furthermore, unilamellar vesicles (UVs) can be further subcategorized based on their size into small unilamellar vesicles (SUVs) with diameters less than 100 nm, large unilamellar vesicles (LUVs) ranging from 100 to 1000 nm, and giant unilamellar vesicles (GUVs) exceeding 1 m in size [26]

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A study published in the Proceedings of the National Academy of Sciences found that aging is associated with a 47% decrease in the catalytic subunit (GCLC) and a 52% decrease in the modulatory subunit (GCLM) of glutamate-cysteine ligase, the rate-limiting enzyme for glutathione production