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Our previously used concentrations of sertraline in pre-clinical in vivo experiments with anti-cancer effects can be extrapolated to the concentrations used in humans, showing a therapeutic index of sertraline that could support future clinical trials [19, 23, 24]

10.1016/j.cbi.2014.09.015 42 EmmaF.MontiniG.ParikhS

A recent study has further elucidated the correlation between neutrophil ferroptosis and SLE pathogenesis, identifying ferroptosis as the predominant mode of neutrophil death (83)

Our goal is to help you better understand your condition, what may have led to its development and what may be continuing to drive it, so that treatment can be more targeted, informed, and effective