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The Reactome pathway Knowledgebase

Mechanisms for this diversity include epigenetic changes, specifically methylation, of the genes encoding these receptors, multiple isoforms of each receptor as a consequence of alternative RNA splicing and multiple sites of translation initiation of receptor mRNA (Hirata et al., 2003

Genetic predisposition Environmental exposure to factors such as cigarette smoke, metal or wood dust, and sand Gastroesophageal reflux Certain viral infections such as hepatitis C and human herpes virus-8 Age What are the Signs and Symptoms of IPF

Briggs Kimberly J, Koivunen P, Cao S, Backus Keriann M, Olenchock Benjamin A, Patel H, Zhang Q, Signoretti S, Gerfen Gary J, Richardson Andrea L, Witkiewicz Agnieszka K, Cravatt Benjamin F, Clardy J, Kaelin William G