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Although RT increases several circulating growth factors that are important for brain health, this review will primarily focus on BDNF and IGF-1, given their prominent role in modulating brain plasticity

Similarly, metabolomic profiling of blood and CSF in patients, alongside microbiome data, can identify which microbial metabolites truly cross into the brain and affect pathways like amyloid deposition or axonal integrity

However, next-generation sequencing (NGS) and mass spectrometry can now amplify and detect the molecules within the vesicles or the intra-vesicular contents of EVs and have revealed several interesting aspects of EVs

Vegetables in the brassica family produce the most glutathione, but the molecule is present in large amounts in several other vegetables