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In clinical samples from patients with glioblastoma, elevated mitochondrial NIX expression levels were identified as a marker of GSCs, and hypoxia-induced elevations in NIX levels were linked to increased ROS-driven NRF2 expression, further contributing to CSC stemness through HIF/mTOR activation 63

[105] Patients should be counseled about potential dizziness and advised to use caution when changing positions or engaging in activities requiring balance