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The genomic loci of rv1127c is adjacent to genes that encode essential enzymes of the methylcitrate cycle (MCC) (methylcitrate synthase (MCS and Rv1131c) and methylcitrate dehydratase (MCD and Rv1130c) and their transcriptional regulator (PrpR and Rv1129c) (Fig

Suzuki K, Doki K, Homma M, Tamaki H, Hori S, Ohtani H, Sawada Y, Kohda Y (2009) Co-administration of proton pump inhibitors delays elimination of plasma methotrexate in high-dose methotrexate therapy