depletion of glutathione in liver hepatic and adenosine by glucocorticoid exposure Wistar rats is pregnancy-independent Full article: Inhibition of glutathione

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Research by Bin Li reveals that SAL activates the AMPK pathway by suppressing miR-802, upregulating p-ACC, CPT-1, and PPAR protein expression while downregulating SREBP-1c, consequently reducing hepatic TG, TC, and LDL-C levels while increasing HDL-C in NAFLD mice, thus modulating lipid metabolism to exert protective effects against NAFLD (Li B

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Histone acetylation and deacetylation are also crucial epigenetic mechanisms which are proven processes that directly impact the DCM pathophysiology in both preclinical and clinical models (128)