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Engineering extracellular matrix-based hydrogels for intervertebral disc regeneration

nitrous oxide exposure can inactivate B12 Important: Do not take folic acid alone when B12 deficiency is possible or uncorrected, as this may worsen neurological damage Avoid measuring serum B12 immediately after injections due to falsely high results Dietary optimisation remains the preferred approach for those without absorption issues

5 Newer tests Most assays for assessing serum vitamin B 12 levels measure cobalamin bound to both transcobalamin II and haptocorrin, that is, total serum cobalamin

- recommend reducing intervention frequency if B12 levels are elevated, and continue to monitor