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However, many other forbidden disulfides share this property, so this does not explain why evolution of CSDs is favored over other forbidden disulfides

Merck Millipore, Burlington, MA, USA) staining was carried out according to the manufacturers instructions

The secondary plot for the first k obs values from the second phase yielded a rate contant at GSSG saturation around 10 s 1 for all three PfGrx variants (Fig