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Potential concerns include: Unknown product quality Contamination or sterility issues Incorrect dosing Injection site reactions Allergic or immune reactions Medication interactions Hormonal or metabolic effects Unclear long-term safety Lack of monitoring Delayed treatment for an actual injury or medical condition Medical oversight is especially important for patients with autoimmune conditions, cancer history, active infections, chronic inflammatory disorders, cardiovascular concerns, hormone-sensitive conditions, or complex medication regimens

According to a STEP 1 study published in the New England Journal of Medicine (NEJM), semaglutide showed significant weight reduction in adults with overweight or obesity